Concepedia

Cesium carbonate mediated exclusive dialkylation of active methylene compounds

Ulaganathan Sankar, C. M. Haricharan Raju, R. Uma

Current Chemistry Letters · 2012 · 13 citations · 28 references

DOIFull text

Open access

Concepts

Abstract

Active methylene compounds are regioselectively dialkylated by variety of alkyl halides using cesium carbonate in quantitative yield. The reaction yielded exclusively dialkylated products with no intermediate monoalkyaltion or mixture of products.

References

28

Water Enables Direct Use of Allyl Alcohol for Tsuji−Trost Reaction without Activators

Hidenori Kinoshita, Hiroshi Shinokubo, Koichiro Oshima · Organic Letters · 2004 · 254 citations

, , +6

Cesium Effect:  High Chemoselectivity in Direct N-Alkylation of Amines

Ralph Nicholas Salvatore, A. S. Nagle, Kyung Woon Jung · The Journal of Organic Chemistry · 2002 · 247 citations

, , +13

An assessment of the causes of the "cesium effect"

Gerard Dijkstra, W. Kruizinga, Richard M. Kellogg · The Journal of Organic Chemistry · 1987 · 247 citations

, , +6

Synthesis of sulfur-containing macrocycles using cesium thiolates

J. BUTER, Richard M. Kellogg · The Journal of Organic Chemistry · 1981 · 163 citations

, , +11

Ionic liquid as catalyst and solvent: the remarkable effect of a basic ionic liquid, [bmIm]OH on Michael addition and alkylation of active methylene compounds

Brindaban C. Ranu, Subhash Banerjee, Ranjan Jana · Tetrahedron · 2006 · 129 citations

, , +9