Clinical Otolaryngology · 2000 · 30 citations · 20 references
Post-operative pain is the main cause of morbidity following tonsillectomy. The efficacy of glossopharyngeal and lesser palatine nerve blocks in controlling postoperative pain in adult patients was investigated prospectively. Patients 16 years and older admitted for elective tonsillectomy were randomised to one of three groups to receive a pre-incisional oropharyngeal injection of 0.5% bupivicaine, a 'dummy' injection of saline or no injection. Dissection tonsillectomy and general anaesthetic techniques were standardized. Postoperative pain was monitored for 24 h. ANOVA, chi2 and Fisher's exact test were used for intergroup comparisons. Ninety-two patients (72 women and 20 men), mean age 22 years were studied. Twenty-nine patients received 0.5% bupivicaine, 30 saline and 33 no pre-incisional injection. The overall mean pain scores of 2.1, 1.9 and 1.9 in the bupivicaine, saline and no injection groups were similar. Glossopharyngeal and lesser palatine 0.5% bupivicaine nerve blocks are not effective in reducing early post-tonsillectomy pain.
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Analysis of serial measurements in medical research.
J. N. S. Matthews, D G Altman, Michael J. Campbell et al. · BMJ · 1990 · 3.1K citations · Full text
Retrospective Cohort Study, Serial Measurements, Medical Research Data +11
Evidence for a central component of post-injury pain hypersensitivity
Clifford J. Woolf · Nature · 1983 · 2.1K citations
Airway Management--Principles and Practice
Allan P. Reed · Anesthesia & Analgesia · 1996 · 186 citations