Dexrazoxane prevents doxorubicin‐induced long‐term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats

Dirk Lebrecht, Andrea Geist, U‐P Ketelsen, Jörg Haberstroh, B. Setzer, Ulrich A. Walker

British Journal of Pharmacology · 2007 · 136 citations · 36 references

DOIFull text

Open access

Abstract

Dexrazoxane prevented doxorubicin induced late-onset cardiomyopathy and also protected the cardiac mitochondria from acquired ultrastructural, genetic and functional damage.

References

36