Synthesis of imidazo[2,1-b][1,3,4]thiadiazole–chalcones as apoptosis inducing anticancer agents

Abstract

A library of imidazothiadiazole–chalcone conjugates were synthesised and investigated for their cytotoxic activity against various human cancer cell lines. Some of the tested compounds like<bold>7a</bold>,<bold>7b</bold>,<bold>11a</bold>and<bold>11b</bold>exhibited promising anticancer activity.