Abnormal expression, highly efficient detection and novel truncations of midkine in human tumors, cancers and cell lines

cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis

Kenji Kadomatsu, Mineko Tomomura, Takashi Muramatsu · Biochemical and Biophysical Research Communications · 1988 · 482 citations

Lineage Plasticity, Developmental Biology, Tumor Heterogeneity +8

An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis.

Rangana Choudhuri, H T Zhang, Sandra Donnini et al. · PubMed · 1997 · 280 citations

Tumor Innervation, Neurokines Midkine, Pathology +17

Midkine, A Retinoic Acid-Inducible Growth/Differentiation Factor: Immunochemical Evidence for the Function and Distribution

Hisako Muramatsu, Hiroshi Shirahama, Suguru Yonezawa et al. · Developmental Biology · 1993 · 228 citations

Developmental Biology, Human Growth, Immunology +10

Serum midkine levels are increased in patients with various types of carcinomas

Shinya Ikematsu, Akira Yano, Kuniaki Aridome et al. · British Journal of Cancer · 2000 · 205 citations · Full text

Solution structure of midkine, a new heparin-binding growth factor

W. Iwasaki · The EMBO Journal · 1997 · 154 citations · Full text

Protein Chemistry, Solution Structure, Protein Function +3