On-line measurement of nitric oxide release from organic nitrates in the intact coronary circulation

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.7K citations

Inflammation, Biological Activity, Endothelium-derived Relaxing Factor +8

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

Reactive Nitrogen Specie, Nitric Oxide, Medicine +8

Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

William P. Arnold, Chandra K. Mittal, Shoji Katsuki et al. · Proceedings of the National Academy of Sciences · 1977 · 1.4K citations · Full text

Nitric Oxide, Various Tissue Preparations, Cellular Physiology +16

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

Richard Palmer, Daryl D. Rees, David Ashton et al. · Biochemical and Biophysical Research Communications · 1988 · 1.3K citations

Molecular Physiology, Biochemistry, Physiological Precursor +9

Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase

Martin Feelisch, E. Noack · European Journal of Pharmacology · 1987 · 897 citations

Bioorganic Chemistry, Biochemistry, Reactive Nitrogen Specie +6