Analysis of Somatostatin Receptors 2 and 5 Polymorphisms in Patients with Acromegaly

Abstract

These data suggest a role for SSTR5 t-461c and c1004t alleles in influencing GH and IGF-I levels in patients with acromegaly, whereas SSTR2 and SSTR5 variants seem to have a minor role in determining the responsiveness to somatostatin analogs.