Anaesthesia · 1990 · 29 citations · 6 references
MedicineAnesthesiologyPharmacologyAnesthesiaCardiovascular PharmacotherapyClinical PharmacologyEndotracheal IntubationHemodynamic Response To AnesthesiaAirway Management MedicationsCaptopril TherapyHeart RateHeart Rate PharmacodynamicsHemodynamic Response To IntubationTracheal Intubation Effects
The effect of sublingual captopril on the pressor response to intubation was studied in 40 patients. Captopril was used in one of two doses (12.5 mg and 25 mg) 25 minutes before tracheal intubation. Both doses were associated with a significant reduction in the pressor response to intubation (p less than 0.05) compared to placebo, but no significant difference existed between the two doses. Neither dose controlled changes in heart rate at intubation. Untoward hypotension occurred in the treatment groups. Caution is advised in the peri-operative use of angiotensin-converting enzyme inhibitors.
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Captopril Reduces the Dose Requirement for Sodium Nitroprusside Induced Hypotension
Jack R. Woodside, Lowell Garner, Robert F. Bedford et al. · Anesthesiology · 1984 · 48 citations · Full text
Anaesthesia and angiotensin‐converting enzyme inhibitors
A. Yates, David N. Hunter · Anaesthesia · 1988 · 40 citations · Full text