BMJ · 1979 · 24 citations · 2 references
MedicineEndocrinologyOncologyBone MetabolismChemotherapyEndocrine OncologyBone MetastasisBreast Cancer PharmacotherapyHormonal Cancer TherapyMalignant NeoplasmsMetastatic Bone DiseaseMetastatic Breast CancerAcute Pain ExacerbationBone Pain In CancerBreast Cancer Endocrine TherapyBreast Cancer Hormonal TherapyBreast Cancer Response AssessmentHormone Therapy ToxicityMetastatic Breast Cancer TreatmentTumor-induced Hypercalcemia
We believe that hypercalcaemia after tamoxifen may signify tumour response and be a reason for continuing with tamoxifen and treating the hypercalcaemia.This is supported by a report of tamoxifen "flare" in metastatic breast cancer and the observation that acute exacerbation of bone pain in patients with breast cancer after tamoxifen may be associated with tumour response.'5The mechanism of tamoxifeninduced tumour response needs further investigation, since acute hypercalcaemia is not seen in patients responding to chemotherapy or oophorectomy.
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Early 67Ga scintigraphy for the localization of abnominal abscesses.
Hopkins Gb, Mende Cw · PubMed · 1975 · 33 citations