Concepedia

Abstract

When both the serum P.B.'3 'I and the thyroid uptake of 13 I are raised, as in two of our cases, distinction from thyrotoxicosis may be achieved by the thyroxine suppression test.The raised serum P.B.'311 may be due in part to the presence of an abnormal iodinated protein in the blood and in part to the unusually rapid production and discharge of hormone from a gland with a low iodine pool.The observation of the effect of potassium perchlorate, which discharges an appreciable amount of the thyroid 1311 content in cases of Hashimoto's thyroiditis, is a useful additional diagnostic aid.Part of this work was carried out during the tenure of an appointment by one of us (1.P. C. M.

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