Curcumol and its one‐step formation from curdione

Abstract

Abstract The absolute stereochemistry of curcumol ( 1 ) is confirmed on the basis of the spectroscopic data. The existence of two conformations in curdione ( 4 ) is revealed by nOe experiments at ambient temperature. One‐step conversion of 4 into 1 stereospecifically proceeds via the ene‐reaction without epimerization at any asymmetric center in 4 .