Ruthenium-Catalyzed Propargylation of Aromatic Compounds with Propargylic Alcohols

Abstract

A novel ruthenium-catalyzed propargylation of aromatic compounds with propargylic alcohols has been found to afford the corresponding propargylated aromatic products in good yields with complete regioselectivity. The catalytic reaction provides a potential usefulness for practical application in organic synthesis, because the selective propargylation of aromatic compounds with an aromatic C-H bond cleavage is generally difficult.