Concepedia

Accumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer

Zhong-Yu Yuan, Luo, Mei Li, Shaoyan Xi, Jia Fu, He

OncoTargets and Therapy · 2013 · 81 citations · 23 references

DOIFull text

Open access

Abstract

Our results suggest that overexpression of p62 in TNBC is associated with a higher risk of distant metastases. This finding could open new avenues for the development of novel therapy strategies for TNBC.

References

23

Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence

Rebecca Dent, Maureen Trudeau, Kathleen I. Pritchard et al. · Clinical Cancer Research · 2007 · 5K citations · Full text

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Geir Bjørkøy, Trond Lamark, Andreas Brech et al. · The Journal of Cell Biology · 2005 · 3.2K citations · Full text

Genes that mediate breast cancer metastasis to lung

Andy J. Minn, Gaorav P. Gupta, Peter M. Siegel et al. · Nature · 2005 · 2.9K citations · Full text

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A multigenic program mediating breast cancer metastasis to bone

Yibin Kang, Peter M. Siegel, Weiping Shu et al. · Cancer Cell · 2003 · 2.6K citations · Full text

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The Triple Negative Paradox: Primary Tumor Chemosensitivity of Breast Cancer Subtypes

Lisa A. Carey, Elizabeth Claire Dees, Lynda Sawyer et al. · Clinical Cancer Research · 2007 · 2.1K citations · Full text