Sustained hippocampal IL-1β overexpression impairs contextual and spatial memory in transgenic mice

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.

W. Sue T. Griffin, Laura Stanley, Lon R. White et al. · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

Immunology, Neurochemical Biomarkers, Glioma +22

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Clinical trial of indomethacin in Alzheimer's disease

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Cognitive Decline, Whereas Placebo Patients, Alzheimer's Disease +13

Arc/Arg3.1 Is Essential for the Consolidation of Synaptic Plasticity and Memories

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Synaptic Plasticity, Cognitive Science, Molecular Neuroscience +12

Experience-Dependent Gene Expression in the Rat Hippocampus after Spatial Learning: A Comparison of the Immediate-Early Genes<i>Arc</i>, c-<i>fos</i>, and<i>zif268</i>

John F. Guzowski, Barry Setlow, Edward K. Wagner et al. · Journal of Neuroscience · 2001 · 693 citations · Full text