Intraperitoneal Injection of Lymphomatous Nerve Tissue into Resistant or Susceptible Chickens

Abstract

INTRODUCTION THE successful selection of two strains of birds differing in their resistance to spontaneous lymphomatosis under the conditions of the parent flock (Hutt, Cole, and Bruckner, 1941, and Taylor et al., 1943), raised the question of whether or not they would retain their relative resistance when exposed to conditions that would produce a large increase in the incidence of the disease. To answer this question it would be necessary to increase the incidence within the parent flock without introducing birds or inocula from other flocks against which the strains had not been selected. This could be accomplished if the incidence within the parent flock could be increased by injecting them with lymphomatous material from affected members of the same flock. The experiments reported in this paper were designed to answer two questions: (1) could the incidence of lymphomatosis among the susceptible and resistant birds be increased by injecting them . . .