Involvement of δ-opioid receptors in the effects of morphine on locomotor activity and the mesolimbic dopaminergic system in mice

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

G. Di Chiara, Assunta Impérato · Journal of Pharmacology and Experimental Therapeutics · 1988 · 922 citations

Medicine, Neuroscience, Pharmacology +17

Naltrindole, a highly selective and potent non-peptide δ opioid receptor antagonist

Philip S. Portoghese, Marjia Sultana, A.E. Takemori · European Journal of Pharmacology · 1988 · 613 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: evidence for delta opioid receptor subtypes.

Mehmet Sofuoglu, Philip S. Portoghese, A.E. Takemori · Journal of Pharmacology and Experimental Therapeutics · 1991 · 340 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Design of peptidomimetic .delta. opioid receptor antagonists using the message-address concept

P. S. Portoghese, Marjia Sultana, A.E. Takemori · Journal of Medicinal Chemistry · 1990 · 259 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.

L G Latimer, Philip E. Duffy, Peter W. Kalivas · Journal of Pharmacology and Experimental Therapeutics · 1987 · 152 citations

Medicine, Neuroscience, Pharmacology +17