International Journal of Infectious Diseases · 2014 · 13 citations · 4 references
Veterinary MedicineImmunologyInfectious DiseasesImmunology Of Infectious DiseasesParasitologyVector-borne DiseasesParasitic Disease PathogenesisParasitic PathogenesisPregnancy ImmunologySand Fly-borne DiseasesT-cell Responses To ParasitesTuberculosis In PregnancyHumoral Immunity ImpairmentImmunopathology Of LeishmaniasisPulmonary Tuberculosis DiagnosisSand Fly TransmissionSand Fly-borne ZoonosesT Helper CellsVisceral LeishmaniasisZoonotic Vector-borne Disease
Visceral leishmaniasis due to Leishmania infantum is a vector-borne zoonotic disease transmitted by sand fly bites endemic in rural or periurban areas of the Mediterranean basin. Pregnancy is accompanied by changes in immune response, mainly a decrease in cellular immunity and a proportional increase in humoral immunity. These physiological events result in increased risk of infection by pathogens whose immunity is based on a T-helper 1 predominant response. We describe a case of visceral leishmaniasis and pulmonary tuberculosis diagnosed in a post-partum woman four days after delivery. The diagnosis of leishmaniasis should be considered in pregnant women with fever and haematologic abnormalities in endemic regions or if a history of exposure in endemic areas is reported.
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Claudia Colomba, Laura Saporito, Valentina Frasca Polara et al. · Transfusion and Apheresis Science · 2005 · 23 citations · Full text
Germano Silva Moura, Alcione Miranda dos Santos, Dorlene Maria Cardoso de Aquino et al. · Cadernos de Saúde Pública · 2012 · 11 citations · Full text