Synergistic effect of apolipoprotein E ε4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease - Concepedia

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Synergistic effect of apolipoprotein E ε4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease

60

Citations

31

References

2008

Year

Roger Lane, Howard Feldman, Joanne M. Meyer, Yunsheng He, Steven H. Ferris, Agneta Nordberg, Taher Darreh‐Shori, Hilkka Soininen, Tuula Pirttilä, Martin R. Farlow,

Pharmacogenetics and Genomics

Abstract

In MCI, the risk of cognitive decline, hippocampal volumetric loss and progression to AD seems to be the greatest in individuals who carry at least one copy of both the BCHE-K and APOE epsilon4 alleles.

References

	Year	Citations

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