IcsA Is a Shigella flexneri Adhesin Regulated by the Type III Secretion System and Required for Pathogenesis

Global burden of Shigella infections: implications for vaccine development and implementation of control strategies.

Karen L. Kotloff, Jonathan P. Winickoff, B Ivanoff et al. · PubMed · 1999 · 1.3K citations · Full text

Veterinary Medicine, Infectious Disease Control, Infectious Diseases +17

Escape of Intracellular <i>Shigella</i> from Autophagy

Michinaga Ogawa, Tamotsu Yoshimori, Toshihiko Suzuki et al. · Science · 2004 · 814 citations

Life Sciences, Infectious Diseases, Microbiology +14

Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin.

Maria Lina Bernardini, Joëlle Mounier, H d'Hauteville et al. · Proceedings of the National Academy of Sciences · 1989 · 727 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells

Robert Ménard, Philippe Sansonetti, Claude Parsot · Journal of Bacteriology · 1993 · 718 citations · Full text

Life Sciences, Genetics, Microbiology +17

Activation of the Cdc42 Effector N-Wasp by the <i>Shigella flexneri</i> Icsa Protein Promotes Actin Nucleation by Arp2/3 Complex and Bacterial Actin-Based Motility

Coumaran Égile, Thomas P. Loisel, Valérie Laurent et al. · The Journal of Cell Biology · 1999 · 523 citations · Full text

Life Sciences, Cell Biology, Microbiology +16