Intracerebroventricular injection of apelin-13 reduces food intake in the rat

Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor

Kazuhiko Tatemoto, Masaki Hosoya, Yugo Habata et al. · Biochemical and Biophysical Research Communications · 1998 · 1.7K citations

Signal Transduction, G Protein-coupled Receptor, Medicine +8

Ghrelin, an Endogenous Growth Hormone Secretagogue, Is a Novel Orexigenic Peptide That Antagonizes Leptin Action Through the Activation of Hypothalamic Neuropeptide Y/Y1 Receptor Pathway

Mitsuyo Shintani, Yoshihiro Ogawa, Ken Ebihara et al. · Diabetes · 2001 · 855 citations · Full text

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

Kazuhiko Tatemoto, Kiyoshige Takayama, Min‐Xu Zou et al. · Regulatory Peptides · 2001 · 639 citations

Hypertension, Neuropeptides, Molecular Physiology +8

Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain

Annabelle Réaux‐Le Goazigo, Nadia De Mota, Ivana Škultétyová et al. · Journal of Neurochemistry · 2001 · 367 citations

Novel Neuropeptide, Cellular Physiology, Rat Brain +26

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

Yugo Habata, Ryo Fujii, Masaki Hosoya et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 1999 · 349 citations

Natural Ligand, Molecular Physiology, Autoimmune Disease +8