EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

François Tronche, Christoph Kellendonk, Oliver Kretz et al. · Nature Genetics · 1999 · 1.9K citations

Life Sciences, Neurobiology, Neuroscience +16

Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3

Fumitaka Ushikubi, Eri Segi‐Nishida, Yukihiko Sugimoto et al. · Nature · 1998 · 687 citations

Life Sciences, Neuroscience, Pharmacology +12

Pathway across the blood–brain barrier

Monica Ek, David Engblom, Sipra Saha et al. · Nature · 2001 · 347 citations

Medicine, Neuroscience, Pharmacokinetics +11

Contrasting Effects of Ibotenate Lesions of the Paraventricular Nucleus and Subparaventricular Zone on Sleep–Wake Cycle and Temperature Regulation

Jian‐Qiang Lu, Y.-H. Zhang, Thomas C. Chou et al. · Journal of Neuroscience · 2001 · 336 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis

David Engblom, Sipra Saha, Linda Engström et al. · Nature Neuroscience · 2003 · 306 citations

Life Sciences, Biochemistry, Immunology +7