Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality

Shock and Tissue Injury Induced by Recombinant Human Cachectin

Kevin J. Tracey, Bruce Beutler, Stephen F. Lowry et al. · Science · 1986 · 2.6K citations

Veterinary Medicine, Immunology, Physiology +17

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

Kevin J. Tracey, Yuman Fong, David Hesse et al. · Nature · 1987 · 2.5K citations

Veterinary Medicine, Immunology, Infectious Diseases +16

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

H. R. Michie, Kirk R. Manogue, David R. Spriggs et al. · New England Journal of Medicine · 1988 · 1.7K citations

Veterinary Medicine, Immunology, Immunophysiology +11

Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxofylline

Robert M. Strieter, Daniel G. Remick, P A Ward et al. · Biochemical and Biophysical Research Communications · 1988 · 561 citations

Life Sciences, Biochemistry, Cell Biology +8

Inhibition of the inflammatory action of interleukin-1 and tumor necrosis factor (alpha) on neutrophil function by pentoxifylline

Gail W. Sullivan, Holliday T. Carper, W J Novick et al. · Infection and Immunity · 1988 · 374 citations · Full text

Veterinary Medicine, Immunology, Immunoregulation +16