Nuclear transcription factor-kappa beta-dependent ultrastructural alterations within the placenta and systemic inflammatory activation in pregnant patients with hemolysis, elevated liver functions and low thrombocyte count (HELLP) syndrome: a case–control study

Yavuz Şimşek, Mehmet Gül, Önder Çelik, Nasuhi Engin Aydın, Senem Arda Düz, Ebru Çelik, Elif Özerol, İbrahim Halil Özerol, Kevser Tanbek

Hypertension in Pregnancy · 2013 · 16 citations · 24 references

Abstract

Our results suggest that over-expression of placental NF-kB is correlated with elevation of serum inflammatory markers and placental ultrastructural changes, which may point to an important role of local and systemic inflammatory activation in the pathogenesis of HELLP syndrome.

References

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