The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

Jean‐Claude Meunier, Catherine Mollereau, Lawrence Toll et al. · Nature · 1995 · 1.9K citations · Full text

Molecular Pharmacology, Endogenous Agonist, Functional Selectivity +8

Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor

Rainer K. Reinscheid, Hans‐Peter Nothacker, Anne Bourson et al. · Science · 1995 · 1.8K citations

Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat

Charles R. Neal, Alfred Mansour, Rainer K. Reinscheid et al. · The Journal of Comparative Neurology · 1999 · 400 citations · Full text

Neurotransmitter, Immunology, Molecular Pain +18

Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: Comparison of ORL1 receptor mRNA expression with125I-[14Tyr]-orphanin FQ binding

Charles R. Neal, Alfred Mansour, Rainer K. Reinscheid et al. · The Journal of Comparative Neurology · 1999 · 341 citations · Full text

Synaptic Signaling, Orphanin Fq Binding, Orphanin Fq +18

Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor

Miyuki Nishi · The EMBO Journal · 1997 · 259 citations · Full text

Nociceptive Response, Health Sciences, Neuroanatomy +11