Development of chromatographic methods for the determination of genotoxic impurities in cloperastine fendizoate

Simultaneous determination of ten antihistamine drugs in human plasma using pipette tip solid‐phase extraction and gas chromatography/mass spectrometry

Chika Hasegawa, Takeshi Kumazawa, Xiao‐Pen Lee et al. · Rapid Communications in Mass Spectrometry · 2006 · 99 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +10

Simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma by liquid chromatography–tandem mass spectrometry

Hao Li, Chao Zhang, Jiang Wang et al. · Journal of Pharmaceutical and Biomedical Analysis · 2009 · 92 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +12

An impact analysis of the application of the threshold of toxicological concern concept to pharmaceuticals

Edward J. Delaney · Regulatory Toxicology and Pharmacology · 2007 · 77 citations

Pharmacy, Toxicology, Mechanisms Of Toxicity +7

Mechanism and Processing Parameters Affecting the Formation of Methyl Methanesulfonate from Methanol and Methanesulfonic Acid: An Illustrative Example for Sulfonate Ester Impurity Formation

Andrew Teasdale, Stephen C. Eyley, Ed Delaney et al. · Organic Process Research & Development · 2009 · 75 citations

Natural Sciences, Chemistry, Pharmaceutical Analysis +11

Genotoxicity profiles of common alkyl halides and esters with alkylating activity

Zhanna Sobol, Maria Engel, Elizabeth Rubitski et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2007 · 72 citations

Pharmacy, Chemistry, Toxicology +12