Association Between Carotid Plaque Characteristics and Subsequent Ischemic Cerebrovascular Events

Norihide Takaya, Chun Yuan, Baocheng Chu, Tobias Saam, Hunter R. Underhill, Jianming Cai, Nam T. Tran, Nayak L. Polissar, Carol Isaac, Marina S. Ferguson,

Stroke · 2006 · 746 citations · 22 references

DOIFull text

Open access

Abstract

Among patients who initially had an asymptomatic 50% to 79% carotid stenosis, arteries with thinned or ruptured fibrous caps, intraplaque hemorrhage, larger maximum %lipid-rich/necrotic cores, and larger maximum wall thickness by MRI were associated with the occurrence of subsequent cerebrovascular events. Findings from this prospective study provide a basis for larger multicenter studies to assess the risk of plaque features for subsequent ischemic events.

References

22