Concepedia

Characterization of mast cell subpopulations in lip cancer

I. Gina Rojas, Loreto Spencer, Alejandra Martínez, M. A. Maurelia, M.I. Rudolph

Journal of Oral Pathology and Medicine · 2005 · 83 citations · 22 references

DOI

Abstract

The results suggest that MC subpopulations may contribute to lip SCC progression. While intratumoral MC(T) may stimulate angiogenesis, peritumoral MC(TC) may promote extracellular matrix degradation and tumor progression at the invasion front.

References

22

Two types of human mast cells that have distinct neutral protease compositions.

Anne‐Marie Irani, Norman M. Schechter, Shirley S. Craig et al. · Proceedings of the National Academy of Sciences · 1986 · 1K citations · Full text

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Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

Lisa M. Coussens, Wilfred W. Raymond, Gabriele Bergers et al. · Genes & Development · 1999 · 943 citations · Full text

, , +15

Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor.

James Blair, Mary J. Marchese, Shuling Ren et al. · Journal of Clinical Investigation · 1997 · 440 citations · Full text

, , +18

Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation.

Barry L. Gruber, Mary J. Marchese, Katsuya Suzuki et al. · Journal of Clinical Investigation · 1989 · 347 citations · Full text

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Activation of human interstitial procollagenase through direct cleavage of the Leu83-Thr84 bond by mast cell chymase.

Juhani Saarinen, Nisse Kalkkinen, Howard G. Welgus et al. · Journal of Biological Chemistry · 1994 · 318 citations · Full text