Anesthesia Awareness and the Bispectral Index

Michael S. Avidan, Lini Zhang, Beth Burnside, Kevin J. Finkel, Adam C. Searleman, Jacqueline A. Selvidge, Leif Saager, Michelle Turner, Srikar Rao, Michael M. Bottros,

New England Journal of Medicine · 2008 · 958 citations · 17 references

DOIFull text

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Abstract

We did not reproduce the results of previous studies that reported a lower incidence of anesthesia awareness with BIS monitoring, and the use of the BIS protocol was not associated with reduced administration of volatile anesthetic gases. Anesthesia awareness occurred even when BIS values and ETAG concentrations were within the target ranges. Our findings do not support routine BIS monitoring as part of standard practice. (ClinicalTrials.gov number, NCT00281489 [ClinicalTrials.gov].).

References

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