New England Journal of Medicine · 2008 · 958 citations · 17 references
We did not reproduce the results of previous studies that reported a lower incidence of anesthesia awareness with BIS monitoring, and the use of the BIS protocol was not associated with reduced administration of volatile anesthetic gases. Anesthesia awareness occurred even when BIS values and ETAG concentrations were within the target ranges. Our findings do not support routine BIS monitoring as part of standard practice. (ClinicalTrials.gov number, NCT00281489 [ClinicalTrials.gov].).
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The Incidence of Awareness During Anesthesia: A Multicenter United States Study
Peter S. Sebel, Andrew Bowdle, Mohammed M. Ghoneim et al. · Anesthesia & Analgesia · 2004 · 712 citations
Awareness during anaesthesia: a prospective case study
Rolf Sandin, Gunnar Enlund, Peter Samuelsson et al. · The Lancet · 2000 · 695 citations