Journal of Endocrinology · 1970 · 19 citations · 0 references
Life SciencesEndocrinologyPhysiologyHormone BiochemistryReproductive EndocrinologySteroid BiochemistryAndrogen PhysiologyFetal PhysiologyGonadal HormonesHormonal InfluencesHormonal RegulationHormonal Regulation Of ReproductionEndocrine Control Of SteroidogenesisFetal Hormonal RegulationSteroidogenesis In Fetal GonadsWolffian Duct Development
SUMMARY In contrast to results in rabbit and dog foetuses, Wolffian duct stabilization in male rat foetuses was inhibited by cyproterone acetate. On the other hand, the stabilizing effect of methyltestosterone in female rat foetuses could be abolished even when excessive androgen doses were given. The hormonal factor(s) involved in normal Wolffian duct stabilization in male rat foetuses remains to be clarified.