DIFFERENTIAL TOXICITY OF CHLOROFORM IN THE MOUSE

A perspective on the role of chemically reactive metabolites of foreign compounds in toxicity—I correlation of changes in covalent binding of reactivity metabolites with changes in the incidence and severity of toxicity

James R. Gillette · Biochemical Pharmacology · 1974 · 226 citations

Pharmacy, Chemistry, Toxicology +16

Chlorinated hydrocarbons and the environment

George. McConnell · Endeavour · 1975 · 182 citations

Pharmacy, Environmental Sciences, Toxicology +10

Chloroform toxicity in mice: Correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules

Kenneth F. Ilett, Watson D. Reid, I.G. Sipes et al. · Experimental and Molecular Pathology · 1973 · 177 citations

Veterinary Medicine, Biochemistry, Toxicology +16

On the Mechanism of the Anti-androgenic Action ofFlutamide (α-α-α-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide)in the Rat

Edwin A. Peets, Margaret Henson, R. Neri · Endocrinology · 1974 · 163 citations

Medicine, Endocrinology, Pharmacology +17

Androgen Receptors in Mouse Kidney: A Study of Male, Female and Androgen-Insensitive (tfm/y) Mice¹

Leslie P. Bullock, C. Wayne Bardin · Endocrinology · 1974 · 149 citations

Life Sciences, Biochemistry, Endocrinology +17