Concepedia

Lung heme oxygenase-1 is elevated in acute respiratory distress syndrome

Sharon Mumby, Rebecca Upton, Yan Chen, Salome J. Stanford, Gregory J. Quinlan, Andrew G. Nicholson, John M.C. Gutteridge, Nicholas J. Lamb, Timothy W. Evans

Critical Care Medicine · 2004 · 100 citations · 17 references

DOI

Abstract

Heme oxygenase protein is elevated in the lungs of patients with ARDS and may contribute to the changes in iron mobilization, signaling, and regulation seen in this condition.

References

17

Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs.

Elizabeth A. Leibold, H. N. Munro · Proceedings of the National Academy of Sciences · 1988 · 684 citations · Full text

, , +19

Reversal of HO‐1 related cytoprotection with increased expression is due to reactive iron

Denise Suttner, Phyllis A. Dennery · The FASEB Journal · 1999 · 415 citations

Heme Oxygenase: Recent Advances in Understanding Its Regulation and Role

Kimberly K. Elbirt, Herbert L. Bonkovsky · Proceedings of the Association of American Physicians · 1999 · 312 citations

, , +19

Exhaled Breath Condensate Isoprostanes Are Elevated in Patients With Acute Lung Injury or ARDS

Chace T. Carpenter, Patricia Price, Brian W. Christman · CHEST Journal · 1998 · 235 citations

, , +8

Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2.

Phyllis A. Dennery, Douglas R. Spitz, Gangyi Yang et al. · Journal of Clinical Investigation · 1998 · 215 citations · Full text

, , +16