Nostocyclyne A, a Novel Antimicrobial Cyclophane from the Cyanobacterium <i>Nostoc</i> sp.

Abstract

A novel acetylene-containing para-[14]-cyclophane, nostocyclyne A (1), possessing antimicrobial activity, is the major active metabolite of the natural bloom of the cyanobacterium Nostoc sp. (TAU strain IL-220). Homonuclear and heteronuclear 2D NMR techniques as well as HREIMS determined the gross structure of 1.