Concepedia

False Positivity of Non-Targeted Infections in Malaria Rapid Diagnostic Tests: The Case of Human African Trypanosomiasis

Philippe Gillet, Dieudonné Mumba Ngoyi, Albert Lukuka, Viktor Kande, Benjamin Atua, Johan van Griensven, Jean‐Jacques Muyembe, Jan Jacobs, Veerle Lejon

PLoS neglected tropical diseases · 2013 · 39 citations · 16 references

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Abstract

Specificity of some malaria RDT products in HAT was surprisingly low, and constitutes a risk for misdiagnosis of a fatal but treatable infection. Our results show the importance to assess RDT specificity in non-targeted infections when evaluating diagnostic tests.

References

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Paracheck-Pf® accuracy and recently treated Plasmodium falciparum infections: is there a risk of over-diagnosis?

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Improved Models of Mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for Sleeping Sickness Diagnosis and Staging

Philippe Büscher, Dieudonné Mumba Ngoyi, Jacques Kaboré et al. · PLoS neglected tropical diseases · 2009 · 126 citations · Full text

<i>Plasmodium falciparum</i> Histidine-Rich Protein 2-Based Immunocapture Diagnostic Assay for Malaria: Cross-Reactivity with Rheumatoid Factors

Jamshaid Iqbal, Ali Sher, Rab A · Journal of Clinical Microbiology · 2000 · 114 citations · Full text