Constitutive Secretion of Interleukin‐6 by Human Decidual Stromal Cells in Culture. Regulatory Effect of Progesterone

Abstract

Basal production of IL-6 by DSC may be involved in physiological functions at the maternal-fetal interface. Nevertheless, the secretion of this cytokine is regulated by progesterone, probably to prevent excessive production of this cytokine from triggering an inflammatory response that might compromise pregnancy.