Identification and quantitation of arsenic species in a dogfish muscle reference material for trace elements

Abstract

The arsenic species present in a dogfish muscle reference material (DORM-1) have been identified by using high-performance liquid chromatography/inductively coupled plasma mass spectrometry (HPLC/ICP-MS), thin-layer chromatography, and electron impact mass spectrometry and quantified by using HPLC/ICP-MS and graphite furnace atomic absorption spectrometry. The major species is arsenobetaine (15.7 ± 0.8 μg of As/g of DORM-1), constituting about 84% of the total arsenic. For this species, the HPLC/ICP-MS detection limit was 0.3 ng of As. © Published 1988 by the American Chemical Society.