Concepedia

Facile synthesis of linear-dendritic cholesteryl-poly(ε-caprolactone)-<i>b</i>-(<scp>l</scp>-lysine)<sub>G2</sub> by thiol-ene and azide-alkyne “click” reactions

Irakli Javakhishvili, Wolfgang H. Binder, Susanne Tanner, Søren Hvilsted

Polymer Chemistry · 2010 · 33 citations · 26 references

DOI

Concepts

Abstract

A rodcoil dendron comprising cholesterol, poly(ε-caprolactone), and dendritic <sc>l</sc>-lysine has been synthesized <italic>via</italic> combination of ring-opening polymerization and sequential orthogonal “click” reactions.

References

26

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.5K citations

, , +8

Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.5K citations

, , +12

Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments

Cole A. DeForest, Brian D. Polizzotti, Kristi S. Anseth · Nature Materials · 2009 · 842 citations

, , +11

Robust, Efficient, and Orthogonal Synthesis of Dendrimers via Thiol-ene “Click” Chemistry

Kato L. Killops, Luis M. Campos, Craig J. Hawker · Journal of the American Chemical Society · 2008 · 781 citations

, , +8

‘Click’ Chemistry in Polymer and Material Science: An Update

Wolfgang H. Binder, Robert Sachsenhofer · Macromolecular Rapid Communications · 2008 · 739 citations · Full text

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