Journal of the American Animal Hospital Association · 1996 · 46 citations · 0 references
Veterinary MedicineVeterinary Internal MedicineVeterinary PathologyBowel ManagementCanine Internal MedicineMucosal ImmunologyCrohn Disease PharmacotherapyGastrointestinal DiseaseGastrointestinal InflammationInflammatory Bowel DiseaseImmunosuppressive CompoundsInflammatory Bowel Disease PathologyInflammatory Bowel Disease TherapyInflammatory Bowel SyndromeNutrition In Ulcerative ColitisPerianal Crohn Disease TherapyPrednisone UseTreatment Protocol Evaluation
Twenty-seven German shepherd dogs with perianal fistulas and histological evidence of colitis were entered in a prospective clinical study to investigate the association between perianal fistula and colitis. Additionally, the response of perianal fistula disease to immunosuppressive doses of prednisone and an alternative protein diet was evaluated. All 27 cases completed the treatment protocol, and perianal fistulas completely resolved in nine (33.3%) cases, improved in nine cases, and remained unchanged in nine cases.