Experimental Biology and Medicine · 1946 · 10 citations · 0 references
Life SciencesEndocrinologyPharmacologyNeuroendocrinologySteroid BiochemistryAdrenal HormonesAdrenal Steroid HormonesAdrenal SteroidogenesisSteroid Hormone BiochemistrySteroid MetabolismSteroidogenesis RegulationGlucocorticoid MetabolismThymus HistologyThymus Histopathology
In short-term experiments, large doses of deoxycorticosterone acetate cause marked thymus atrophy. Thus it appears that this effect is not the exclusive characteristic of the glucocorticoids and furthermore that the nonspecific damage of D.C.A. has not been operative since the result was obtained in adrenalectomized rats.