FDA guidelines and animal models for osteoporosis

The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates.

R. Balena, Brian C. Toolan, M. Shea et al. · Journal of Clinical Investigation · 1993 · 399 citations · Full text

Medicine, Animal Sciences, Endocrinology +17

The bisphosphonate, alendronate, prevents bone loss in ovariectomized baboons

David D. Thompson, J.G. Seedor, H. Quartuccio et al. · Journal of Bone and Mineral Research · 1992 · 103 citations · Full text

Medicine, Endocrinology, Bone Metabolism +14

Maintaining restored bone with bisphosphonate in the ovariectomized rat skeleton: Dynamic histomorphometry of changes in bone mass

W.S.S. Jee, Li Tang, Hua Zhu Ke et al. · Bone · 1993 · 42 citations

Medicine, Endocrinology, Orthopedic Surgery +16