Myocardial perfusion defects in right ventricular apical pacing are caused by partial volume effects because of wall motion abnormalities: a new model to study gated myocardial SPECT with the pacemaker on and off

Abstract

Despite a fixed amount of tracer activity in the myocardium, larger and more perfusion defects were visible during RVA pacing compared with normal conduction. The site and severity of the perfusion defects correlates with abnormal wall motion because of this pacing mode. This implies that abnormal wall motion is at least partly responsible for the apparent myocardial perfusion defects.