Increased expression and mutation of p53 in choroidal melanoma

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.1K citations

Engineering, Dna Analysis, Molecular Biology +19

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

J L Cordell, Brunangelo Falini, Wendy N. Erber et al. · Journal of Histochemistry & Cytochemistry · 1984 · 3.2K citations

Immunocytochemical Technique, Immunology, Alkaline Phosphatase +24

Mutations in the p53 gene occur in diverse human tumour types

Janice Nigro, Suzanne J. Baker, Antonette C. Preisinger et al. · Nature · 1989 · 2.8K citations · Full text

Tumor Biology, Somatic Variant, Tumor Heterogeneity +7

The p53 proto-oncogene can act as a suppressor of transformation

Cathy A. Finlay, Philip W. Hinds, Arnold J. Levine · Cell · 1989 · 2K citations

Cell Regulation, Oncogenic Agent, P53 Proto-oncogene +6