Inhibition of PARP1 by small interfering RNA enhances docetaxel activity against human prostate cancer PC3 cells

Cancer Statistics, 2010

Ahmedin Jemal, Rebecca L. Siegel, Jiaquan Xu et al. · CA A Cancer Journal for Clinicians · 2010 · 12.6K citations · Full text

Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer

Ashish Juvekar, Laura N. Burga, Hai Hu et al. · Cancer Discovery · 2012 · 475 citations · Full text

Dual Roles of PARP-1 Promote Cancer Growth and Progression

Matthew J. Schiewer, Jonathan F. Goodwin, Sumin Han et al. · Cancer Discovery · 2012 · 439 citations · Full text

Akt: A Double-Edged Sword in Cell Proliferation and Genome Stability

Naihan Xu, Yuanzhi Lao, Yaou Zhang et al. · Journal of Oncology · 2012 · 303 citations · Full text

Dna Damage, Genetics, Cell Death +20

Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination–Defective Cells

Ponnari Gottipati, Barbara Vischioni, Niklas Schultz et al. · Cancer Research · 2010 · 218 citations

Genome Instability, Parp Hyperactivity, Natural Sciences +8