Transdermal Fentanyl

Abstract

I Transdermal Therapeutic Systems - An Introduction.- Transdermal Permeation: Physiological and Physicochemical Aspects.- Transdermal Therapeutic Systems in Clinical Use: Development and Applications.- II Current Aspects of Pain Management.- Postoperative Pain.- Cancer Pain.- Pain Management and Quality of Life in Cancer Patients.- Opioid Analgesia for Chronic, Nonmalignant Pain.- III Noninvasive Fentanyl Application.- Pharmacokinetics of Fentanyl.- Premedication and Pain Management with Oral Transmucosal Fentanyl.- Transdermal Fentanyl: an Overview of Pharmacokinetics, Efficacy and Safety.- IV Postoperative Pain Management with TTS Fentanyl.- Pharmacokinetics and Pharmacodynamics.- Clinical Experience.- Respiratory Safety.- TTS Fentanyl in Combination with Patient-Controlled Analgesia.- V Cancer Pain Management with TTS Fentanyl.- Clinical Experience.- VI Other Transdermal Therapeutic Systems for Anesthesia and Pain Management.- Local Anesthetics: Eutectic Mixture of Local Anesthetics.- Scopolamine.