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A cryptic PKS–NRPS gene locus in the plant commensal Pseudomonas fluorescens Pf-5 codes for the biosynthesis of an antimitotic rhizoxin complex
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Citations
14
References
2007
Year
BiologyBiosynthesisPlant-microbe InteractionNatural SciencesAntimitotic Rhizoxin ComplexMolecular BiologyPlant Commensal PseudomonasGene InactivationMicrobiologyPf-5 CodesMetabolic ProfilingMolecular MicrobiologyMedicineMicrobial Genetics
Targeted gene inactivation and metabolic profiling revealed that the cryptic PKS-NRPS gene cluster in the genome of the plant commensal Pseudomonas fluorescens Pf-5 codes for the biosynthesis of antiproliferative and antifungal rhizoxin derivatives.
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