Concepedia
Bioorganic & Medicinal Chemistry Letters · 2014 · 47 citations · 16 references
PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryStructure-activity RelationshipsSynthetic Medicinal ChemistryCarboxylic AcidsLead Compound DesignNatural Product Drug DiscoveryOrganic AcidsPyrazole Chemistry
16
An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)
Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text
Medicine, Medicinal Chemistry, Pharmacology +14
Improvement in Glucose Tolerance and Insulin Resistance in Obese Subjects Treated with Troglitazone
John J. Nolan, Bernhard Ludvik, P. Beerdsen et al. · New England Journal of Medicine · 1994 · 935 citations · Full text
Medicine, Endocrinology, Pharmacology +15
Studies on Antidiabetic Agents. X. Synthesis and Biological Activities of Pioglitazone and Related Compounds.
Yū Momose, Kanji Meguro, Hitoshi Ikeda et al. · Chemical and Pharmaceutical Bulletin · 1991 · 288 citations · Full text
Pharmacy, Medicinal Chemistry, Pharmacology +13
Effects of Troglitazone: A new hypoglycemic agent in patients with NIDDM poorly controlled by diet therapy
Yasuhiko Iwamoto, Kinori Kosáka, Takeshi Kuzuya et al. · Diabetes Care · 1996 · 180 citations
Medicine, Pharmacology, Pharmacotherapy +16
The vilsmeier-haack reaction - III Cyclization of hydrazones to pyrazoles
Mitsuo Kira, M.O. Abdel-Rahman, K. Z. Gadalla · Tetrahedron Letters · 1969 · 165 citations
Natural Sciences, Chemistry, Medicinal Chemistry +8