Inhibition of urate production by allopurinol

On the Mechanism of Inactivation of Xanthine Oxidase by Allopurinol and Other Pyrazolo[3,4-d]pyrimidines

Vincent Massey, Hirochika Komai, Graham Palmer et al. · Journal of Biological Chemistry · 1970 · 385 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

A comparison of the specificities of xanthine oxidase and aldehyde oxidase

Thomas A. Krenitsky, Shannon M. Neil, Gertrude B. Elion et al. · Archives of Biochemistry and Biophysics · 1972 · 342 citations

Life Sciences, Biochemistry, Biocatalysis +3

The Mechanism of Action of Xanthine Oxidase

John S. Olson, David P. Ballou, Graham Palmer et al. · Journal of Biological Chemistry · 1974 · 335 citations · Full text

Life Sciences, Biochemistry, Chemistry +17

Metabolic studies of allopurinol, an inhibitor of xanthine oxidase

Gertrude B. Elion, Aylene Kovensky, George H. Hitchings et al. · Biochemical Pharmacology · 1966 · 331 citations

Life Sciences, Biochemistry, Pharmacology +6

Renal clearance of oxipurinol, the chief metabolite of allopurinol

Gertrude B. Elion, Ts’ai-Fan Yű, Alexander B. Gutman et al. · The American Journal of Medicine · 1968 · 202 citations

Pharmacy, Pharmacokinetics, Pharmacology +11