Concepedia

Rational design of an optical adenosine sensor by conjugating a DNA aptamer with split DNAzyme halves

Na Lü, Congying Shao, Zhaoxiang Deng

Chemical Communications · 2008 · 75 citations · 46 references

DOI

Concepts

Abstract

Split halves of a hemin-binding DNAzyme have been assembled with an anti-adenosine aptamer to build a homogeneous allosteric sensor for adenosine with high selectivity and sensitivity.

References

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