The Rh System

Abstract

Abstract. A consanguineous ♂R 1 R 2 × ♀R 1 R 1 mating is reported which produced one child, four R 1 R 1 and two R 1 R 2 children. Nonpaternity and nonmaternity are ruled out as an explanation for the anomalous phenotype. The authors produce evidence indicating that this is indistinquishable from heritable and deduce from that it is, therefore, identical with that gene. Three explanations are offered for its occurrence here and two discarded. The third is a mutation: they favor the hypothesis that in this they are seeing the expression of a ‘gene of control’ and its effect on a ‘gene of structure’ in the complex that is Rh.