Forkhead box P3‐positive regulatory T‐cells and interleukin 17‐positive T‐helper 17 cells in chronic inflammatory periodontal disease

Abstract

These results show that FOXP3(+) cells are more prominent than IL-17(+) cells in periodontal disease processes, which may suggest a predominant role for FOXP3(+) cells in periodontal disease. Further studies are required to characterize these cells more precisely and to understand, in more detail, their roles in the pathophysiology of periodontal disease.