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Synthesis and Application of Some New Thienopyrimidine Derivatives as Antimicrobial Agents
36
Citations
7
References
1996
Year
Medicinal ChemistryBioorganic ChemistryHeterocyclicSeveral DerivativesNatural SciencesMedicineCorresponding 4-Chloro DerivativeOrganic ChemistryAntimicrobial ActivityAntibacterial AgentNew Thienopyrimidine DerivativesChemistryAntimicrobial AgentsHeterocycle ChemistryPharmacologyAntimicrobial CompoundDerivative (Chemistry)Synthetic Chemistry
Abstract The paper describes the synthesis of new ring system 5-phenylthieno[2,3-d]pyrimidine-4(3H)one (2). Chlorination of (2) with PCl5, POCl3 gave the corresponding 4-chloro derivative (4). Several derivatives of the latter compound have been synthesised and tested for antimicrobial activity.
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